Miraculous Microbes: Cancer Fighting Bacteria and Alluring Yeast

Miraculous Microbes: Cancer Fighting Bacteria and Alluring Yeast

Nature is weird. Very weird. It turns out there is viral and fungal infections that make plants more attractive to bees and other insect pollinators. This allows the virus or fungi to jump from plant to plant transmitting the infection. Are these infections then bad news, as they first appear?

Lets start with the virus. Viruses are often seen as the evil bad guys, trying to thwart life at every turn – their name comes from the Latin vīrus referring to poison and other noxious liquids. In reality however viruses actually do a lot for us and our world and despite being often defined as ‘disease-causing agents’ (as bacteria first were). The Cucumber Mosaic Virus infects lots of plants (not just cucumbers confusingly), stunting their growth and damaging their fruits. However it also makes them far more attractive to pollinators, increasing their chancing of fruiting. More fruit = more baby plants. This is only one example of how viruses aren’t all bad and how many are harmless or even helpful to their hosts. 

Fantastical Fungi

Next is the fungi, yeast. Fungi aren’t just the stuff that rots our food, causes disease and grows in our uni houses (well in mine at least). Fungi are crucial to us and our world: recycling the dead into nutrients so that plants can grow; allowing us to brew beer and rise bread; giving us our first antibiotics, including penicillin (made by sensibly named Penicillium fungi) and a whole host of other medicines; providing natural pesticides, protecting our crops. Maybe most amazingly,  fungi form a network made up of trillions of miles of small white hair-like fungi, called Mycorrhiza, that link to the roots of most plants. This network provides most of the world’s grasses and trees with crucial nutrients and minerals in return for food, in a super symbiosis known as the wood wide web. It may even allow trees and plants to communicate – another post coming soon. 

There is a another amazing fungal talent that scientists have found, that may bring down the price of our weekly shops. Yeast are single celled fungal microorganisms that eat sugars, converting them to alcohol. Nectar in flowers is a sugary soup which is a bonanza for yeast. The only problem is the feast is boom and bust, as the flowers don’t last long, dooming the yeast to a slow death if they don’t get out (which is hard seeing their singled celled and cant move*). One species of yeast, Metschnikowia Reukaufii, has been shown to attract bees, enabling it to hitch a ride from one flower to the next, helping the flower sexually reproduce. 

Scientists don’t fully understand why the Mosaic Virus or Metschnikowia make plants sexy. Currently scientists think that the infections do this to increase the spread of the easier-infected plants throughout the population, breeding more suitable victims that it can infect. Their also not sure how they attract pollinators either actually, it could be the yeast releases an attractive chemical, or just doesn’t release unpleasant ones (like other yeast). We simply don’t know, It’s worth finding out though, because by understanding the infections that enhance pollination scientists hope to one day use modified yeast and viruses to get bees to target crops and plants that we want to pollinate – improving crop yields and bringing down fruit and veg prices for everyone.

The Cancer fighting Bacteria

Could a bacteria stop the side effects of cancer treatment? Clostridium sporogenes is a soil bacteria which could in the future be used to deliver toxic cancer drugs only to the cancerous tumour, rather than the whole body, reducing their crippling side effects. In nature, the bacteria is only found in soil with no oxygen – which is why they are so useful. Solid tumors (which cause cancers such as breast, brain and prostate) don’t contain oxygen (unlike every other tissue in the human body), so the microbes can only survive there when injected into the human body, where they multiply. In the near future scientists hope to genetically engineer them to carry cancer drugs, making them perfect delivery system. These soil-living superheroes could make the side effects of treatment a thing of past .

Other magnetic soil bacteria may also provide targets drug treatments. As magnetic bacteria can already swim (with their flagella) and have magnets inside them, the plan is to direct them towards the target cells using a controlled magnetic fields.

3) https://www.omicsonline.org/open-access/magnetotactic-bacteria-and-their-application-in-medicine-2161-0398.1000141.php?aid=26389

*Yeast can move about, but seeing they are so small a cm would seem more like a mile to these microbes.